Figure 3 | Scientific Reports

Figure 3

From: Clinical and Genetic Characteristics of 18 Patients from 13 Japanese Families with CRX-associated retinal disorder: Identification of Genotype-phenotype Association

Figure 3The alternative text for this image may have been generated using AI.

Spectral-domain optical coherence tomographic images from 18 patients with CRX-RD. Spectral-domain optical coherence tomographic images demonstrate outer retinal disruption at the macula in eight subjects (Patients 1, 3, 4–6, 8, 15, 18). Outer retinal disruption at the peri-macula is observed in 12 subjects (Patients 1–6, 8, 13–15, 17, 18). Intraretinal micro-cystic changes are noted in Patient 13. Epiretinal membrane is found in Patient 8. Marked preservation of the photoreceptor ellipsoid zone (EZ) line at the fovea is identified in eight subjects (Patients 2, 5, 7, 10–14), and slightly preserved EZ at the fovea isobserved in three subjects (Patients 9, 16, 17). Preserved foveal structure surrounded by parafoveal atrophy (i.e., bull’s eye pattern) is found in six subjects (Patients 1, 2, 10, 11, 12, 17).

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