Figure 3 | Scientific Reports

Figure 3

From: Spatio-temporal patterning of different connexins in developing and postnatal human kidneys and in nephrotic syndrome of the Finnish type (CNF)

Figure 3

Co-expression of different Cxs with CD31 and α –SMA in CNF kidneys. (a–l) CNF post-natal kidneys (3,5 years). Cx43, Cx40 and Cx37 expression (arrows), and CD31 and α –SMA is expression (arrows), glomeruli (g), proximal tubules (pt) and distal tubules (dt), cysts of proximal tubules (c), blood vessels (bv) and interstitium (i). DAPI nuclear staining (c,g,k). Merged microphotographs of different Cxs with CD31 and α –SMA show their co-expression (arrowhead) in the wall of blood vessels and population of interstitial myofibroblasts (mf) (d,h,l). Double immunofluorescence staining of DAPI with Cx43 /Cx45 (a–d) x100; DAPI with Cx37/CD31 (e–h) x20, and DAPI with Cx40/α –SMA x100. (m) Fluorescence intensity histograms comparing healthy and CNF postnatal kidneys.

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