Figure 4
From: CircRNA_101237 promotes NSCLC progression via the miRNA-490-3p/MAPK1 axis
miR-490-3p inhibited NSCLC progression via MAPK1. (A) Bioinformatics tools helped to find that miR-490-3p and MAPK1 3ʹ-UTR saw the existence of complementary binding sites. (B,C) Luciferase reporter assay confirmed that miR-490-3p and MAPK1 3ʹ-UTR exhibited molecular binding in A549 cells (B) and H1299 cells (C). (D,E) qRT-PCR assay found the existence of mRNA MAPKP level in indicated NSCLC cells. *P < 0.05; **P < 0.01; ***P < 0.001.
