Figure 1 | Scientific Reports

Figure 1

From: Clinical relevance and functional significance of cell-free microRNA-1260b expression profiles in infiltrative myxofibrosarcoma

Figure 1

Global screening of circulating/extracellular miRNA in patients and MFS cell culture media. (A) Heatmap and the hierarchical clustering of miRNA microarray analysis using serum samples collected from MFS patients in preoperative state (MFS), age-matched benign tumor patients (NON), and healthy individuals (CONT). (B) Serum levels of four upregulated miRNAs in (A). *p < 0.05, **p < 0.01; Student’s t test. (C) The expression levels of extracellular miR-642a, miR-1260b, and miR-4286 in MFS cell culture media (NMFH-1 and NMFH-2) compared to human mesenchymal stem cells (hMSCs). Data are presented as mean ± S.D. (n = 3 in each group) *p < 0.05, **p < 0.01; Student’s t test. (D) The expression levels of extracellular miR-1260b in the culture media of NMFH-1 and NMFH-2 cells based on cell number and the culture duration. Data are presented as mean ± S.D. (n = 3 in each group) *p < 0.05; Student’s t test.

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