Figure 5

All experimental groups of mice are capable of displaying investigatory sniffing upon novel stimulus presentation which then habituates over repeated trials. The instantaneous respiration frequency during the mineral oil presentations was calculated by the same method used to derive the time spent engaged in investigatory sniffing during odor presentations. Graphs A-C show that female mice in both treatment groups (PBS - black and PFFs - gray) respond with investigatory sniffing upon the first mineral oil trial which then habituates over the repeated exposures at one- (a), three- (b) and six-months (c) post- injection. Horizontal dashed line = 6 Hz respiratory frequency indicator.