Figure 7
Histopathological feature of carotid body lesions. (A) Location of the CB at the bifurcation point of the common carotid artery (CCA) in its internal and external branches. The surrounding tissue is represented by striated muscle (left part of the image) and autonomic ganglion (AG) (embedded in connective tissue). The arrow indicates the focal to extensive coagulative area of necrosis affecting the autonomic ganglion and adjacent tissue. (B) Focal to extensive coagulative necrosis was present in AG; and central chromatolysis, perikaryon eosinophilia, vacuolation and karyopyknosis were identified (indicated by the arrows). (C) Focal to extensive coagulative necrosis, congestion and hemorrhage (indicated by the grey arrow) that extended to the adjacent walls (indicated by the black arrow). (D) Presence of focal rhabdomyolysis (myonecrosis) with loss of visible cross-striations, sarcoplasmic fragmentation, karyopyknosis and karyorrhectic nuclei near the periphery of the CB (indicated by the black arrows). The endomysial space is dilated, edematous, with discrete neutrophil and macrophage infiltration (indicated by the grey arrow).
