Figure 1 | Scientific Reports

Figure 1

From: Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

Figure 1

Mean levels (±SEM) of anti-WT, GTKO, and TKO pig IgM and IgG in various primate species (A), and summarized as human, OWM, and NWM (B). (A) Comparison of binding of preformed xenoreactive antibodies in various primate species (human [n = 9], baboon [n = 6], rhesus [n = 6], cynomolgus [n = 6], African green [n = 6], capuchin [n = 9] and squirrel monkey [n = 6]) to WT (left), GTKO (middle), and TKO (right) pig PBMCs. IgM (top) and IgG (bottom). Results are expressed as mean ± SEM. (*p < 0.05, **p < 0.01). (B) Comparison of binding of preformed xenoreactive antibodies in humans [n = 9], OWMs [n = 24], and NWMs [n = 15] to WT (left), GTKO (middle), and TKO (right) pig PBMCs. IgM (top) and IgG (bottom). Results are expressed as mean ± SEM. (*p < 0.05, **p < 0.01).

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