Figure 4 | Scientific Reports

Figure 4

From: Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

Figure 4

Correlation of human (n = 9, black), OWM (n = 24, blue), and NWM (n = 15, red) serum IgM (upper) and IgG (lower) antibody binding with serum complement-dependent cytotoxicity (CDC, at 25% serum concentration) to WT (left), GTKO (middle), and TKO (right) pig PBMCs. On the y axis, the dotted line represents cut-off value (6.4%) below which there is no cytotoxicity. On the x axis, the dotted line represents cut-off value (IgM:1.2, IgG:1.1) below which there is no binding. (*p < 0.05, **p < 0.01). (Note the difference in scale on the x axis between IgM and IgG. Note the difference in scale on the x axis between TKO and others).

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