Table 2 Pig to baboon kidney transplantation (pig genetic engineering, recipient survival, and causes of death).
Baboon Number | Donor pig genetic engineered phenotype | Survival(days) | Cause of Death |
|---|---|---|---|
TKO group (N = 3) | |||
B3917 | TKO/CD46/CD55/TBM/EPCR/CD47/HO1 | 1 | HAR |
B2416 | TKO/CD46/CD55/TBM/EPCR/CD47/HO1 | 4 | acute gastric dilatation |
B1417 | TKO/CD46/CD55/TBM/EPCR/CD47/HO1 | 61 | AHXR |
GTKO group (N = 5) | |||
B3115 | GTKO/CD46/hvWF | 4 | acute gastric dilatation |
B10815 | GTKO/CD46/TBM/EPCR/CD47/HO1 | 90 | AHXR |
B9315 | GTKO/CD46/CD55/TBM/EPCR/CD39 | 136 | infection |
B17315 | GTKO/CD46/CD55/EPCR/TFPI/CD47 | 237 | infection |
B17615 | GTKO/CD46/CD55/EPCR/TFPI/CD47 | 260 | Infection |
