Table 4 Hazard ratio (HR) and corresponding 95% confidence interval (CI) for HPV-driven tumors vs non-HPV-driven tumors. SPT: second primary tumor

From: Age-independent increasing prevalence of Human Papillomavirus-driven oropharyngeal carcinomas in North-East Italy

Survival outcome

Crude estimatesa

Adjusted estimatesb

HR

(95% CI)

HR

(95% CI)

Mucosal control

0.10

(0.02–0.44)

0.14

(0.03–0.61)

Regional control

0.18

(0.05–0.60)

0.28

(0.08–1.02)

Locoregional control

0.11

(0.03–0.36)

0.16

(0.05–0.52)

Distant control

0.66

(0.16–2.67)

1.64

(0.31–8.72)

SPT controlc

0.09

(0.01–0.70)

0.10

(0.01–0.83)

Progression-free survival

0.22

(0.11–0.42)

0.27

(0.13–0.54)

Overall survival

0.25

(0.12–0.49)

0.33

(0.16–0.67)

  1. aAdjusted for gender, age and year of diagnosis. bFurther adjusted for T status, N status, and alcohol drinking. cIncluding only cancer of the head and neck, oesophagus and lung.
Back to article page