Table 1 Circulating white blood cells (neutrophils, lymphocytes, monocytes, eosinophils, and basophils) in dairy calves with increased serotonin bioavailability.

From: Increasing serotonin bioavailability alters gene expression in peripheral leukocytes and lymphoid tissues of dairy calves

WBC count

Treatmentsa

P-valueb

CON

5-HTP

FLX

5-HTP vs. CON

FLX vs. CON

Neutrophils, 103/μL

3.69 ± 0.62

3.96 ± 0.67

3.69 ± 0.62

0.78

0.99

Monocytes, 103/μL

1.08 ± 0.11

1.19 ± 0.12

0.97 ± 0.11

0.51

0.48

Lymphocytes, 103/μL

4.37 ± 0.23

4.79 ± 0.24

4.79 ± 0.23

0.22

0.48

Eosinophils, 103/μL

0.06 ± 0.02

0.06 ± 0.22

0.09 ± 0.02

0.96

0.42

Basophils, 103/μL

0.01 ± 0.02

0.05 ± 0.03

0.03 ± 0.02

0.26

0.71

  1. aOral supplementation of milk replacer with saline (control; n = 8), fluoxetine (40 mg/d; n = 8) or 5-hydroxytryptophan (5-HTP, 90 mg/d; n = 8) to Holstein dairy calves for 10 consecutive days.
  2. bStatistical significance declared at P-value ≤ 0.05 and tendencies at 0.05 < P ≤ 0.10.
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