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Figure 1

From: Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

Figure 1

RNA Sequencing of Human Cardiac Fibroblasts on Bioscaffolds. (A) Selected genes associated with cardiac fibrosis are downregulated in human cardiac fibroblasts on intact bioscaffolds relative to matched cells on neutralized bioscaffolds (N = 4 subjects/group). (B) Genes associated with blood vessel assembly are upregulated in human cardiac fibroblasts on intact bioscaffolds relative to matched cells on neutralized scaffolds (N = 4 subjects/group). Values reported are group mean ± SD. All represented data had false discovery rate corrected-P values <0.05 as determined using the Benjamin-Hochberg procedure for multiple comparisons. Illustrations were prepared using MindtheGraph software (www.mindthegraph.com) and used under the creative commons license (https://creativecommons.org/licenses/by-sa/4.0/deed.en).

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