Figure 7 | Scientific Reports

Figure 7

From: Acellular bioscaffolds redirect cardiac fibroblasts and promote functional tissue repair in rodents and humans with myocardial injury

Figure 7

Human Bioscaffold Therapy Improves Myocardial Perfusion of Infarcted Myocardium. (A) Representative cardiac MRI images of the left ventricle at baseline, 6 weeks, and 6 months post-op. Arrows indicate site of perfusion defect. (B) We illustrate that late tissue perfusion is differentially increased in myocardial regions with implanted bioscaffolds. We quantified regional myocardial perfusion and compared LV regions for each patient between 6 weeks and 6 months post-op. We used the anterior wall as a region with coronary bypass but without bioscaffolds. We used the inferior as a region without coronary bypass but with bioscaffold implantation. (C) We compared regional myocardial perfusion relative to global LV perfusion for both patients between 6 weeks and 6 months post-op.

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