Table 1 Experimental factors for biosynthesis of AgNPs and corresponding levels.

From: Central Composite Design for Optimizing the Biosynthesis of Silver Nanoparticles using Plantago major Extract and Investigating Antibacterial, Antifungal and Antioxidant Activity

Independent variable

Variable levels

Star-low (−α) (−2)

Low (−1)

Center (0)

High (+1)

Star-high (+α) (+2)

Temperature (°C)

10

25

40

55

70

pH

5.5

7

8.5

10

11.5

Vex (ml)

0.5

1.5

2.5

3.5

4.5

Vex (ml)

15

20

25

30

35

Time (min)

0

60

120

180

240

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