Table 3 Predicted proportions of hypertension, obesity and diabetes by age at follow-up in women according to weight for gestational age in first offspring.

From: Life Course Trajectories of Maternal Cardiovascular Risk Factors according to Offspring Birthweight: The HUNT Study

 

Predicted proportion among women with AGAb offspring

Difference between SGAc and AGA proportions

Difference between LGAd and AGA proportions

Percent

(95% CI)

Percentage points

(95% CI)

Percentage points

(95% CI)

Hypertension

20 years

5.8

(4.6, 7.4)

2.4

(−1.1, 6.0)

0.4

(−3.6, 4.4)

30 years

5.8

(5.2, 6.4)

0.7

(−0.8, 2.1)

−0.4

(−2.3, 1.6)

40 years

13.5

(12.6 ‒ 14.4)

2.3

(0.2, 4.4)

1.0

(−2.1, 4.2)

50 years

33.6

(32.0 ‒ 35.2)

4.9

(1.4, 8.5)

3.1

(−2.5, 8.7)

60 years

57.6

(54.9 ‒ 60.2)

3.6

(−1.2, 8.4)

5.6

(−2.2, 13.3)

Obesity

20 years

2.9

(2.3, 3.5)

−0.6

(−1.6, 0.4)

5.0

(1.9, 7.9)

30 years

6.8

(6.0, 7.7)

−0.04

(−1.6, 1.5)

4.7

(1.9, 7.4)

40 years

8.5

(7.7, 9.3)

−1.8

(−3.1, −0.6)

5.2

(2.5, 7.9)

50 years

9.7

(8.8, 10.7)

−2.1

(−3.5, −0.7)

3.3

(0.4, 6.2)

60 years

11.6

(10.3, 13.2)

−1.6

(−3.8, 1.0)

2.6

(−1.9, 7.0)

Diabetes

20 years

0.4

(0.1, 1.0)

−0.2

(−0.8, 0.5)

0.1

(−0.8, 1.0)

30 years

0.4

(0.2, 0.6)

−0.2

(−0.5, 0.03)

1.6

(0.3, 2.9)

40 years

0.9

(0.7, 1.1)

−0.4

(−0.9, 0.04)

1.8

(0.4, 3.3)

50 years

1.5

(1.1, 1.9)

−0.3

(−1.0, 0.3)

1.3

(−0.3, 2.9)

60 years

3.4

(2.5, 4.4)

−0.9

(−2.3, 0.6)

1.9

(−1.5, 5.4)

  1. aPopulation average proportions are estimated with all covariates set at their means and as if the woman has her first birth at age 23. All estimates are adjusted for age at measurement, maternal height, smoking status, educational status, HUNT survey and age at first birth.
  2. bAGA was defined as birthweight ≥10th and ≤90th centile for the Norwegian population.
  3. cSGA was defined as birthweight below the 10th centile and for the Norwegian population.
  4. dLGA was defined as birthweight above the 90th centile for the Norwegian population.