Table 2 Presenting tumor characteristics between NAFLD, HBV and HCV.

From: Improved survival after treatments of patients with nonalcoholic fatty liver disease associated hepatocellular carcinoma

 

NAFLD

HBV

HCV

P value

Within Milan (%)

85 (68)

79 (46)

109 (69)

<0.0001

Within UCSF (%)

100 (80)

93 (55)

128 (81)

<0.0001

Median first tumor size (cm) (IQR)

2.9 (2–4.5)

4 (2.4–7.6)

3 (2.1–4.6)

0.0003

Median tumor numbers (IQR)

1 (1–2)

1 (1–2)

1 (1–2)

0.232

AFP-producers

35 (35)

111 (66)

124 (76)

<0.0001

Most definitive therapy*, n (%):

OLT

50 (40)

19 (11)

30 (19)

<0.001

Resection

14 (11)

37 (22)

14 (9)

 

RFA

26 (21)

20 (12)

24 (15)

 

TACE/Y-90

13 (10)

27 (16)

26 (15)

 

PEI

0 (0)

2 (1)

6 (4)

 

Chemotherapy

5 (4)

14 (8)

4 (3)

 

Supportive

17 (14)

51 (30)

55 (35)

 
  1. IQR = interquartile range; AFP = alpha-fetoprotein; RFA = radiofrequency ablation; TACE = trans-arterial chemoembolization; OLT = orthotopic liver transplantation.
  2. *Total group not sub-divided by OLT before or after 2000.