Table 5 Cox multivariable analysis of patients and treatment variables associated with overall survival and recurrence free survival (n = 454).
Variable | HR | 95% CI | P value |
|---|---|---|---|
Overall Survival | |||
Male gender | 0.16 | 0.88–1.54 | 0.2891 |
Age (per year) | 0.99 | 0.98–1.01 | 0.0741 |
Etiologies: | |||
HCV vs HBV | 0.96 | 0.68–1.34 | 0.8118 |
NAFLD vs HBV | 0.35 | 0.15–0.80 | 0.0134 |
NAFLD vs HCV | 0.37 | 0.17–0.77 | 0.0034 |
Race/Ethnicity | |||
African American | Ref | — | — |
White | 0.66 | 0.23–1.89 | 0.4379 |
Asian | 0.74 | 0.26–2.05 | 0.5568 |
Hispanic | 0.9 | 0.30–2.68 | 0.8478 |
Not Hispanic | 1.52 | 0.39–5.86 | 0.5451 |
Most definitive treatment: | |||
Chemotherapy | Ref | — | — |
OLT (after year 2000) | 0.08 | 0.04–0.17 | <0.0001 |
OLT (before year 2000) | 0.11 | 0.04–0.27 | <0.0001 |
PEI | 0.36 | 0.14–0.92 | 0.0338 |
Resection | 0.15 | 0.08–0.29 | <0.0001 |
RFA | 0.16 | 0.08–0.30 | <0.0001 |
TACE | 0.45 | 0.26–0.79 | 0.0055 |
Supportive care | 0.83 | 0.49–1.42 | 0.5 |
Recurrence Free Survival | |||
Male gender | 1.12 | 0.90–1.51 | 0.245 |
Age (per year) | 0.99 | 0.98–1.01 | 0.0626 |
Etiologies: | |||
HCV vs HBV | 1.08 | 0.78–1.49 | 0.6504 |
NAFLD vs HBV | 0.69 | 0.39–1.39 | 0.3002 |
NAFLD vs HCV | 0.64 | 0.34–1.20 | 0.163 |
Ethnicity: | |||
African American | Ref | — | — |
White | 0.76 | 0.27–2.18 | 0.6104 |
Asian | 0.91 | 0.33–2.53 | 8608 |
Hispanic | 0.92 | 0.31–2.71 | 0.8734 |
Not Hispanic | 0.84 | 0.24–2.93 | 0.7824 |
Most definitive treatment: | |||
Chemotherapy | Ref | — | — |
OLT (after year 2000) | 0.09 | 0.05–0.17 | <0.0001 |
OLT (before year 2000) | 0.11 | 0.04–0.28 | <0.0001 |
PEI | 0.38 | 0.15–0.98 | 0.0461 |
Resection | 0.24 | 0.14–0.44 | <0.0001 |
RFA | 0.28 | 0.16–0.51 | <0.0001 |
TACE | 0.54 | 0.31–0.93 | 0.0276 |
Supportive Care | 0.75 | 0.43–1.26 | 0.2749 |