Figure 1

Observed (squares) and physiologically based pharmacokinetic (PBPK) model-stimulated (lines) plasma concentration-time profile of dabigatran and ticagrelor: (a) dabigatran 150 mg oral (b) ticagrelor 200 mg oral.

Observed (squares) and physiologically based pharmacokinetic (PBPK) model-stimulated (lines) plasma concentration-time profile of dabigatran and ticagrelor: (a) dabigatran 150 mg oral (b) ticagrelor 200 mg oral.