Table 2 Allele frequency and genotype analysis.
From: Relationship between the characteristic traits of polycystic ovary syndrome and susceptibility genes
Nearest genes | SNP | Chr. | A1/A2 | MAF | OR (95% CI) | P | |
|---|---|---|---|---|---|---|---|
PCOS | Control | ||||||
FSHB | rs11031006 | 11 | A/G | 0.0587 | 0.0436 | 1.37 (1.02, 1.83) | 3.31 × 10−2 |
FSHR | rs2268361 | 2 | G/A | 0.510 | 0.478 | 1.14 (1.00, 1.29) | 4.67 × 10−2 |
LHCGR | rs10176989 | 2 | C/A | 0.218 | 0.264 | 0.78 (0.67, 0.90) | 9.68 × 10−4 |
TOX3 | rs11075466 | 16 | G/A | 0.377 | 0.319 | 1.29 (1.13, 1.47) | 1.73 × 10−4 |
RAB5B | rs705704 | 12 | A/G | 0.248 | 0.207 | 1.26 (1.09, 1.49) | 2.47 × 10−3 |
KHDRBS3 | rs10505648 | 8 | G/A | 0.056 | 0.090 | 0.59 (0.46, 0.77) | 3.66 × 10−5 |
YAP1 | rs1894116 | 11 | G/A | 0.200 | 0.168 | 1.24 (1.46, 2.59) | 9.04 × 10−3 |
THADA | rs13429458 | 2 | A/C | 0.171 | 0.190 | 0.88 (0.75, 1.04) | 1.26 × 10−1 |
DENDD1A | rs2479106 | 9 | G/A | 0.252 | 0.244 | 1.04 (0.90, 1.22) | 5.78 × 10−1 |
INSR | rs2059807 | 19 | G/A | 0.293 | 0.292 | 1.00 (0.87, 1.15) | 9.56 × 10−1 |
C9orf3 | rs4385527 | 9 | A/G | 0.202 | 0.214 | 0.93 (0.80, 1.09) | 3.93 × 10−1 |
SUMO1P1 | rs6013809 | 20 | A/C | 0.382 | 0.351 | 1.15 (1.00, 1.30) | 4.23 × 10−2 |
