Table 3 Free testosterone levels in relation to genotypes in the PCOS group. Data are presented as the geometric means (95% CI). 9.56 × 10−1.

From: Relationship between the characteristic traits of polycystic ovary syndrome and susceptibility genes

Nearest gene

SNP

Genotype

n

Free testosterone

(ng/dL)

P

FSHB

rs11031006

GG

762

0.75 (−0.33, −0.26)

1.94 × 10−3

  

AA + AG

100

0.84 (−0.23, −0.04)

 

FSHR

rs2268361

AA

205

0.72 (−0.29, −0.22)

0.060

  

GG + GA

657

0.77 (−0.29, −0.22)

 

LHCGR

rs10176989

AA

602

0.78 (−0.40, −0.28)

6.90 × 10−3

  

CC + CA

260

0.71 (−0.028, −0.21)

 

TOX3

rs11075466

AA

337

0.75 (−0.34, −0.24)

0.50

  

GG + GA

525

0.77 (−0.31, −0.23)

 

RAB5B

rs705704

GG

471

0.77 (−0.30, −0.22)

0.35

  

AA + GA

391

0.74 (−0.34, −0.25)

 

KHDRBS3

rs10505648

AA

767

0.75 (−0.31, −0.24)

0.62

  

GG + GA

95

0.80 (−0.35, −0.16)

 

YAP1

rs1894116

AA

551

0.77 (−0.30, −0.22)

0.19

  

GG + GA

311

0.74 (−0.36, −0.25)

 

THADA

rs13429458

CC

335

0.78 (−0.43, −0.14)

0.12

  

AA + AC

518

0.74 (−0.31, −0.24)

 

DENDD1A

rs2479106

AA

463

0.72 (−0.35, −0.27)

0.020

  

GG + GA

399

0.80 (−0.28, −0.19)

 

INSR

rs2059807

AA

426

0.75 (−0.31, −0.22)

0.51

  

GG + GA

436

0.77 (−0.33, −0.24)

 

C9orf3

rs4385527

GG

554

0.76 (−0.31, −0.23)

0.62

  

AA + AG

305

0.77 (−0.34, −0.23)

 

SUMO1P1

rs6013809

CC

334

0.75 (−0.34, −0.24)

0.47

  

AA + AC

520

0.76 (−0.31, −0.23)

 
  1. All results were adjusted for age and body mass index.
  2. CI, confidence interval; PCOS, polycystic ovary syndrome; SNP, single nucleotide polymorphism.