Table 1 Sixteen groups of MT1A and MT2A SNP combinations of MT1A rs11640851, MT1A rs8052394, MT2A rs10636, and MT2A rs28366003, according to wild types and variant types.
Group | Principle of the combination | MT1A2A combination | Case number | Percentage (%) |
|---|---|---|---|---|
1 | Wild-Wild-Wild-Wild | CCAAGGAA | 20 | 4.1 |
2 | Variant-Wild-Wild-Wild | AAAAGGAA, ACAAGGAA | 77 | 15.9 |
3 | Wild-Variant-Wild-Wild | CCAGGGAA, CCGGGGAA | 46 | 9.5 |
4 | Wild-Wild-Variant-Wild | CCAACCAA, CCAAGCAA | 14 | 2.9 |
5 | Wild-Wild-Wild-Variant | CCAAGGAG | 32 | 6.6 |
6 | Variant-Variant-Wild-Wild | AAAGGGAA, ACAGGGAA, ACGGGGAA | 55 | 11.3 |
7 | Variant-Wild-Variant-Wild | AAAACCAA, AAAAGCAA, ACAACCAA, ACAAGCAA | 67 | 13.8 |
8 | Variant-Wild-Wild-Variant | AAAAGGAG, ACAAGGAG | 6 | 1.2 |
9 | Wild-Variant-Variant-Wild | CCAGGCAA, CCGGGCAA | 23 | 4.7 |
10 | Wild-Variant-Wild-Variant | CCAGGGAG, CCAGGGGG | 5 | 1.0 |
11 | Wild-Wild-Variant-Variant | CCAACCAG, CCAACCGG, CCAAGCAG | 5 | 1.0 |
12 | Variant-Variant-Variant-Wild | AAAGCCAA, AAAGGCAA, AAGGGCAA, ACAGCCAA, ACAGGCAA, ACGGGCAA | 79 | 16.3 |
13 | Variant-Variant-Wild-Variant | ACAGGGAG | 6 | 1.2 |
14 | Variant-Wild-Variant-Variant | AAAACCAG, AAAAGCAG, ACAACCAG, ACAAGCAG | 28 | 5.8 |
15 | Wild-Variant-Variant-Variant | CCAGCCAG, CCAGCCGG, CCAGGCAG, CCGGCCAG, CCGGGCAG | 10 | 2.1 |
16 | Variant-Variant-Variant-Variant | AAGGGCAG, ACAGCCAG, ACAGGCAG, ACGGGCAG | 12 | 2.5 |
Total | 485 | 100 |
