Table 2 Descriptive analysis of the demographic characteristics, biomarker levels, and MT1A and MT2A SNPs.

From: The association of blood lead levels and renal effects may be modified by genetic combinations of Metallothionein 1A 2A polymorphisms

 

Mean ± SD

Medium

IQR (25%-75%)

Age (years)

42.40 ± 7.99

43.20

37.04–48.55

Job duration (years)

12.94 ± 7.80

11.23

7.03–16.17

Body height (cm)

162.28 ± 8.21

162.50

156.00–168.70

Body weight (kg)

62.09 ± 11.18

61.20

53.45–70.20

Body mass index (kg/m2)

23.49 ± 3.31

23.32

21.10–25.40

Systolic blood pressure (mmHg)

123.19 ± 17.01

121.00

112.00–133.00

Diastolic blood pressure (mmHg)

76.81 ± 10.96

76.00

69.00–83.00

Current blood lead (μg/dL)

22.30 ± 13.34

21.10

11.80–31.00

Index of cumulative lead (μg/ × yr/dL)

339.82 ± 304.62

259.90

116.70–449.34

Time-weighted ICL (μg/dL)

24.98 ± 12.71

24.59

15.32–33.03

Serum uric acid (mg/dL)

6.37 ± 1.53

6.20

5.20–7.30

Serum creatinine (mg/dL)

0.95 ± 0.22

0.90

0.80–1.10

Urinary creatinine (mg/dL)

190.11 ± 97.62

174.00

127.00–241.00

Urinary uric acid (mg/g Cr)

36.88 ± 16.63

34.87

24.87–47.18

Urinary NAG (mg/g Cr)

3.13 ± 1.88

2.66

1.94–3.78

Gender

Case Number (%)

  

   Female (%)

212 (43.71%)

  

   Male (%)

273 (56.29%)

  

Smoking

Case Number (%)

  

   Yes (%)

183 (37.73%)

  

   No (%)

302 (62.27%)

  

Drinking

Case Number (%)

  

   Yes (%)

75 (15.46%)

  

   No (%)

410 (84.53%)

  

MT1A, rs11640851

Case Number (%)

(HWE, p = 0.447)

 

   AA

99 (20.41%)

  

   AC

231 (47.63%)

  

   CC

155 (31.96%)

  

MT1A, rs8052394

Case Number (%)

(HWE, p = 0.631)

 

   AA

249 (51.34%)

  

   AG

194 (40.00%)

  

   GG

42 (8.66%)

  

MT2A, rs10636

Case Number (%)

(HWE, p = 0.508)

 

   GG

247 (50.93%)

  

   GC

194 (40.00%)

  

   CC

44 (9.07%)

  

MT2A, rs28366003

Case Number (%)

(HWE, p = 0.179)

 

   AA

381 (78.56%)

  

   AG

101 (20.82%)

  

   GG

3 (0.62%)

  
  1. IQR: Interquartile range; HWE: Hardy-Weinberg equilibrium.