Figure 1

Saliva microbiota alpha- and beta diversity from 2-days to 18 years of age. Amplicon sequence variant (ASV) based diversities built on results from 924 saliva samples collected at ages 2-days, 3- and 18-months and 3-, 5- and 18-years. Figures a-c show rarefaction curves (alpha diversity) based on (a) observed amplicon sequence variants (ASVs), (b) Faith’s phylogenetic diversity and (c) Shannon index at varying sequencing depths. Figures (d,e) show PCoA plots illustrating beta-diversity based on (d) Jaccard diversity, and (e) Unweighted Unifrac distance for the same ASVs. The first component explained nearly 14% based on the Jaccard diversity of the individual variation and 34% based on the Unweighted Unifrac distance.