Table 1 Characteristics of the included children (2 days to 5 years of age) and of the included young adults (18 year of age).

From: A longitudinal study of the development of the saliva microbiome in infants 2 days to 5 years compared to the microbiome in adolescents

 

2 days

3 months

18 months

3 years

5 years

18 years

n = 207a

n = 159

n = 141

n = 141

n = 119

n = 175

Boys, %

53.1

54.1

57.9

55.1

51.3

51.4

Age, mean (95% CI)

3.1 (2.8, 3.3)

18.0 (17.9, 18.3)

2.9 (2.7, 3.3)

5.0 (4.8, 5.2)

18.1 (18.0, 18.3)

Caesarean section, %

6.9

Breastfedb, %

98.5

82.4

5.0

2.0

0.0

Antibioticsc, n (%)

1 (0.5)

4 (2.5)

9 (6.5)

1 (0.7)

3 (2.5)

0 (0)

Probiotic drops, %

17.5

4.7

Use of pacifier, %

69.0

65.5

43.2

0.8

Daily tooth brushingd, %

96.5

99.1

80.0

Caries, %

8.8

10.0

69.7

defs/DeFS, mean (95% CI)

1.2 (1.1, 2.0)

2.7 (1.3, 5.0)

4.7 (3.7, 5.8)

Illumina analysise, n

206

155

132

140

116

175

  1. aAppropriate sampling was not possible for 3 infants.
  2. bExclusive or partial breast-feeding.
  3. cChildren receiving antibiotics within 3 months before sampling. For the 18-year-old subjects, antibiotic use within 6 months prior to sampling was an exclusion criterium.
  4. dDaily brushing refers to brushing 1–2 times per day.
  5. eNumbers after exclusion of participants that received antibiotics within 3 months prior to sampling.