Figure 2 | Scientific Reports

Figure 2

From: Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia

Figure 2

ECG characteristics of HCN4-CNBD and Nav1.5+/− mice under basal conditions. 24 h heart rate and PR interval in WT (black circle) and HCN4-CNBD (green circle, A,B) together with the corresponding representative samples of telemetric ECG recordings (WT in C, HCN4-CNBD in D). 24 h averaged value of PR (E) and QRS (F) intervals recorded in WT (black circle) and Nav1.5+/− (gray bars) mice. G: Close up of two superimposed ECG complexes from WT (black line) and Nav1.5+/− (gray circle) mouse. Statistics: unpaired t test. Error bars define the s.e.m.

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