Table 3 Statistical analysis of AVBII reduction before (Pre) and after (Post) injection of tertiapin-Q (Tert), atropine (Atro), isoprenaline (Iso) and theophylline (Theo) in Cav1.3−/− mice.

From: Inhibition of G protein-gated K+ channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia

 

Tert

5 mg/kg

(A)

Atro

0.5 mg/kg

(B)

Iso

mg/kg

(C)

Theo

10 mg/kg

(D)

p

A

B

C

D

Pre

20/4

14/6

11/3

4/4

<0.0001

0.0256

0.6776

>0.9999

Post

5/19

6/14

9/5

3/4

  1. Number of mice with AVBII/number of mice without AVBII; statistics: Fisher’s exact test.
Back to article page