Table 1 Clinical characteristics and outcome data.

From: Epstein-Barr virus reactivation in sepsis due to community-acquired pneumonia is associated with increased morbidity and an immunosuppressed host transcriptomic endotype

Characteristic

Epstein-Barr virus-negative (n = 459)

Epstein-Barr virus-positive (n = 271)

p-value

Age (years)

60.5 (17–92)

62.4 (19–91)

0.11

Male sex^

275 (60%)

141 (52%)

0.049

Charlson comorbidity index*

2.8 (0–10)

2.6 (0–9)

0.30

ICU-acquired infection^

87 (19%)

66 (24%)

0.098

Mortality (28-day)§

72 (16%)

64 (24%)

0.051

Intensive care unit length of stay§ (days)

9.2 (1–101)

12.9 (1–55)

0.0040

Sequential Organ Failure Assessment score (day 1)*

5.9 (0–17)

6.9 (1–19)

0.00011

Sequential Organ Failure Assessment score (maximum over the first 7 days of admission)*

6.7 (0–19)

7.9 (1–21)

3.6 × 10−6

  1. Epstein-Barr virus-negative and Epstein-Barr virus-positive individuals are compared (total n = 730). Intensive care unit length of stay analysis only includes patients surviving to intensive care unit discharge. T-test performed except where indicated (^Chi-squared test; *Mann-Whitney U-test; §Log-rank test). Summary values refer to the mean. The range of values observed is provided where relevant.
Back to article page