Table 3 Recurrence-free survival information according to selected clinical and molecular factors.
Characteristic | Number of cases | Number of events | 5-year recurrence-free survival | p-value (log-rank) |
|---|---|---|---|---|
HPV status | ||||
Negative | 33 | 11 | 48.8% | 0.082 |
Positive | 18 | 3 | 75.5% | |
Tobacco history | ||||
never | 7 | 0 | 100.0% | 0.045 |
current/former | 44 | 14 | 50.2% | |
Mutation status (any gene) | ||||
WT | 19 | 3 | 80.0% | 0.156 |
mutated | 32 | 11 | 47.9% | |
PTEN status | ||||
WT | 47 | 11 | 64.5% | 0.045 |
mutated | 4 | 3 | 25.0% | |
NOTCH1 status | ||||
WT | 40 | 8 | 68.2% | 0.032 |
mutated | 11 | 6 | 35.1% | |
TP53 status | ||||
WT | 28 | 5 | 75.9% | 0.137 |
mutated | 23 | 9 | 42.6% | |
EAp53 | ||||
WT/low-risk | 37 | 7 | 71.8% | 0.080 |
high-risk | 11 | 6 | 38.4% | |