Table 1 Summary of demographic, clinical, and laboratory findings of COVID-19 patients on admission. Highest HRCT score, HRCT peak day and treatments in the clinical course are also included.
Normal Range | Pneumonia (n = 61) | Severe Pneumonia (n = 38) | p - value | |
|---|---|---|---|---|
Demographics | ||||
Age, years | 53 (35 ~ 67) | 64 (57 ~ 69) | 0.003 | |
Sex | ||||
Male | 23 (38%) | 22 (58%) | 0.079 | |
Female | 38 (62%) | 16 (42%) | ||
Comorbidities | 21 (34%) | 28 (74%) | 0.0003 | |
Hypertension | 15 (25%) | 19 (50%) | 0.018 | |
Cardiovascular disease | 6 (10%) | 4 (11%) | 1.0 | |
Diabetes | 6 (10%) | 9 (24%) | 0.19 | |
Cerebrovascular disease | 1 (2%) | 1 (3%) | 1.0 | |
COPD | 1 (2%) | 1 (3%) | 1.0 | |
Asthma | 1 (2%) | 1 (3%) | 1.0 | |
Malignancy | 1 (2%) | 0 (0%) | 1.0 | |
Chronic liver disease | 1 (2%) | 0 (0%) | 1.0 | |
Signs and Symptoms | ||||
Fever | 48 (79%) | 34 (89%) | 0.267 | |
Cough | 43 (70%) | 33 (87%) | 0.103 | |
Dyspnea | 30 (49%) | 29 (76%) | 0.014 | |
Anorexia and/or Lethargy | 13 (21%) | 19 (50%) | 0.006 | |
Fatigue | 15 (25%) | 22 (58%) | 0.002 | |
Myalgia and/or Arthralgia | 9 (15%) | 7 (18%) | 0.84 | |
Diarrhoea | 8 (13%) | 4 (11%) | 0.76 | |
Laboratory Findings | ||||
White blood cell count (×109/L) | 3.5 ~ 9.5 | 4.4 (3.35 ~ 5.46) | 5.15 (3.80 ~ 6.72) | 0.089 |
Neutrophil count (×109/L) | 1.8 ~ 6.3 | 2.73 (1.81~3.78) | 3.7900 (2.5575~5.1700) | 0.005 |
Lymphocyte count (×109/L) | 1.1 ~ 3.2 | 1.23 (0.91 ~ 1.52) | 0.775 (0.59 ~ 1.08) | 1.768e-05 |
Neutrophil/Lymphocyte | 2.14 (1.51 ~ 3.43) | 4.80 (3.02 ~ 7.60) | 2.237e-06 | |
D-dimer (μg/L) | 0 ~ 1 | 0.35 (0.18 ~ 0.76) | 0.67 (0.37 ~ 1.62) | 0.002 |
Lactate dehydrogenase (U/L) | 103 ~ 227 | 168 (153 ~ 219) | 250 (195.75 ~ 360.5) | 3.929e-06 |
C-reactive protein (mg/dL) | 0 ~ 0.6 | 0.73 (0.33 ~ 2.46) | 4.2 (2.47 ~ 7.31) | 1.143e-06 |
Radiographic Findings | ||||
Highest HRCT score | 10 (7 ~ 16) | 24.5 (19.0 ~ 31.5) | 3.556e-12 | |
Peak day | 12 (9 ~ 15) | 14 (11 ~ 18) | 0.048 | |
