Table 2 The most highly up- and down-regulated genes in hDFC induced to undergo osteoblastic differentiation.
Ensembl ID | Gene symbol | Gene name | Fold-change | p-value |
|---|---|---|---|---|
Up-regulated genes | ||||
ENSG00000105664 | COMP | cartilage oligomeric matrix protein | 8.58 | 0.013 |
ENSG00000154556 | SORBS2 | sorbin and SH3 domain-containing 2 | 6.60 | 0.013 |
ENSG00000136160 | EDNRB | endothelin receptor type B | 6.43 | 0.013 |
ENSG00000117152 | RGS4 | regulator of G protein signalling 4 | 5.99 | 0.024 |
ENSG00000103888 | KIAA1199 | Cell migration inducing hyaluronidase 1 | 5.50 | 0.013 |
ENSG00000116741 | RGS2 | regulator of G protein signaling 2 | 5.23 | 0.013 |
ENSG00000196611 | MMP1 | matrix metalloproteinase 1 | 5.14 | 0.013 |
ENSG00000118113 | MMP8 | matrix metalloproteinase 8 | 5.02 | 0.031 |
ENSG00000159167 | STC1 | stanniocalcin-1 | 4.93 | 0.013 |
ENSG00000073756 | PTGS2 | prostaglandin-endoperoxide synthase 2 | 4.93 | 0.013 |
ENSG00000178919 | FOXE1 | forkhead box E1 | 3.26 | 0.038 |
ENSG00000166670 | MMP10 | matrix metalloproteinase10 | 3.04 | 0.013 |
ENSG00000103175 | WFDC1 | WAP four-disulfide core domain 1 | 2.68 | 0.038 |
ENSG00000137331 | IER3 | immediate early response 3 | 2.62 | 0.013 |
Down-regulated genes | ||||
ENSG00000128165 | ADM2 | adrenomedullin 2 | −3.08 | 0.013 |
ENSG00000135069 | PSAT1 | phosphoserine aminotransferase 1 | −3.66 | 0.013 |
ENSG00000204291 | COL15A1 | collagen type V alpha 1 chain | −6.89 | 0.013 |