Figure 3
From: Hydrogel-based milliwell arrays for standardized and scalable retinal organoid cultures
Electron micrographs of Crx-GFP-derived retinas at 25 days. 50 nm ultra-thin sections were imaged by standard EM section of resin embedded retinal organoids. (A) Retinal-like section exhibits characteristic cone morphologies with several polymorphic heterochromatin foci (representative examples shown with arrowheads). The insert highlights cone inner segments. Scale bar: 10 μm. (B) A PR inner segment with mitochondria (mt), a centriole (ct), a basal body (bb) and outer limiting membrane (olm). (C) Classical array of nine triplet and doublet microtubles of bb and transiction zone (tz) of the cc respectively. (D) A PR with a connecting cilium (cc) bearing a rudimentary outer segment, the ciliary vesicle (cv). Scale bars (B,C) = 500 nm.
