Figure 3
From: Mesenchymal Stromal Cell Bioreactor for Ex Vivo Reprogramming of Human Immune Cells

Secreted Factors following Perfusion of Activated PBMCs through MSC-Bioreactor Circuits. PBMCs activated with PHA (5 ug/mL) and supplemented with IL-2 (100 ng/mL) were perfused through bioreactor circuits containing 0 M or 9 M (n = 3) and medium was recovered. Both (A) factor concentration and (B) extracellular vesicle characteristics were modulated with MSC treatment.