Table 6 Modularity structure in IBS patients and healthy controls.

From: Resting state functional connectivity of the pain matrix and default mode network in irritable bowel syndrome: a graph theoretical analysis

Sendai cohort

   

HC

   

L/R amygdala

L/R hippocampus

L/R middle insula

 

L/R angular gyrus

L/R pACC

L/R thalamus

 

L/R anterior insula

L/R vlPFC

L/R precuneus

 

L LTC

PAG

L IPL

 

L/R PCC

L posterior insula

L parahippocampal gyrus

 

L/R putamen

L pMCC

R posterior insula

 

L SI

R IPL

R SI

 

L SII

R LTC

R pMCC

 

L/R aMCC

R SII

  

L/R dlPFC

   

L/R mPFC

   

R parahippocampal gyrus

   

L/R sACC

   

IBS

   

L/R amygdala

L/R angular gyrus

L/R PCC

L/R posterior insula

L/R hippocampus

L/R IPL

L/R aMCC

L/R putamen

L/R anterior insula

L/R thalamus

L/R dlPFC

L/R SII

L/R middle insula

L/R pACC

L/R precuneus

L/R mPFC

L/R vlPFC

L LTC

L sACC

R pMCC

L parahippocampal gyrus

L pMCC

R parahippocampal gyrus

 

L/R SI

R sACC

  

PAG

   

R LTC

   

Gothenburg cohort

   

HC

   

L/R angular gyrus

L/R hippocampus

L/R middle insula

 

L/R LTC

L/R IPL

L/R posterior insula

 

L/R mPFC

L/R thalamus

L/R PCC

 

L/R precuneus

L/R SI

L/R putamen

 

L amygdala

L/R pACC

L/R SII

 

L sACC

L anterior insula

L/R aMCC

 

R dlPFC

L dlPFC

L/R parahippocampal gyrus

 
 

R pMCC

L/R vlPFC

 
  

L pMCC

 
  

PAG

 
  

R amygdala

 
  

R anterior insula

 
  

R sACC

 

IBS

   

L/R amygdala

L/R angular gyrus

L/R posterior insula

 

L/R hippocampus

L/R LTC

L/R PCC

 

L/R anterior insula

L/R SI

L/R aMCC

 

L/R IPL

L/R SII

L/R dlPFC

 

L/R putamen

L/R parahippocampal gyrus

L/R mPFC

 

L/R thalamus

L/R vlPFC

L/R pACC

 
 

L middle insula

L/R pMCC

 
 

PAG

L/R precuneus

 
  

L/R sACC

 
  

R middle insula

 
  1. IBS, irritable bowel syndrome; L, left; R, right; IPL, inferior parietal lobule; LTC, lateral temporal cortex; PCC, posterior cingulate cortex; SI/SII, primary/secondary somatosensory cortex; aMCC, anterior midcingulate cortex; dlPFC, dorsolateral prefrontal cortex; mPFC, medial prefrontal cortex; pACC, pregenual anterior cingulate cortex; pMCC, posterior midcingulate cortex; sACC, subgenual anterior cingulate cortex; vlPFC, ventrolateral prefrontal cortex; PAG, periaqueductal grey matter.