Figure 2 | Scientific Reports

Figure 2

From: Efficient uptake and retention of iron oxide-based nanoparticles in HeLa cells leads to an effective intracellular delivery of doxorubicin

Figure 2

Morphological characterization of HeLa cells after IONP treatment. Bright-field images of HeLa cells incubated for 16 h with: (a) PBS; (b) DOX (1.11 μg/mL equivalent concentration to IONPDOX; Supplementary data Section 2); (c) IONPCO (100 μg/mL) and (d) IONPDOX (100 μg/mL); IONP are stained blue after Prussian Blue staining, 40x magnification (oil). Fluorescence images of HeLa cells 24 h after incubation for 16 h with: (e) 100 μg/mL or IONPDOX. Nuclei are stained with DAPI (blue), red staining is fluorescence from incorporated DOX; 40x magnification.

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