Table 1 Areas with stronger activation in patients with ADSD before BoNT-A treatment when compared to healthy controls.

L-sided stimulation						R-sided stimulation
V1						V1
Area	x	y	z	t	V	Area	x	y	z	t	V
−	−					L primary somatosensory, face (BA2)	−54	−20	32	4.78	760
						L supramarginal (BA40)	−60	−34	24	4.58
						L superior parietal (BA7)	−54	−38	46	4.20
						L superior temporal (BA22)	−58	−42	16	3.80
						L secondary somatosensory (OP1)	−64	−20	22	3.63
						L intraparietal sulcus	−42	−50	58	3.59
						L superior parietal (BA5)	−32	−52	56	3.21
						L dorsal insula (BA13)	−32	28	2	4.39	348
						L ventral insula (BA13)	−38	18	−10	4.23
V2						V2
Area	x	y	z	t	V	Area	x	y	z	t	V
R primary somatosensory, face (BA3b)	54	−8	44	4.98	364	L primary somatosensory, face (BA1)	−58	−14	42	4.34	411
R primary motor/ ventral premotor (BA4/6)	42	−4	58	3.79		L primary somatosensory, face (BA2)	−50	−20	36	3.63
R inferior frontal (BA44)	36	26	0	4.37	346	L intraparietal sulcus (BA40)	−26	−48	42	4.00
R ventral premotor (BA6)	46	4	10	3.61		L secondary somato- sensory (OP4)	−64	−16	20	4.51	396
R dorsal insula	40	2	6	3.67		L superior temporal (BA22)	−64	−44	14	4.41
						L supramarginal (BA40)	−64	−32	22	4.28
Ha						Ha
Area	x	y	z	t	V	Area	x	y	z	t	V
R primary somatosensory, hand (BA2)	30	−36	66	4.46	1135	−	−
R primary somatosensory, face (BA1)	56	−18	44	4.03
R intraparietal sulcus (BA7)	28	−58	60	3.91
R superior parietal (BA5/7)	18	−54	64	3.73
R secondary somatosensory (OP4)	58	−16	18	3.51
R supramarginal (BA40)	36	−36	42	3.32

Coordinates (in mm) in the Montreal Neurological Institute space. All differences are significant at p_FWEc< 0.0083 at a cluster-forming threshold of p < 0.001 uncorrected. BA, Brodmann area; OP, operculum parietale; R, right; L, left; t, t-score; V, cluster volume (voxels).

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