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Figure 1

From: Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

Figure 1

ABA improves glycemic control in a diet-induced model of obesity. Wild-type C57BL/6 mice treated with fig extract ABA (0.125 µg ABA/kg body weight) or vehicle during 12 weeks of 42% kcal from fat diet (TD.88137, Envigo). Intraperitoneal glucose tolerance test (2 g/kg) was conducted at 10 weeks of HFD feeding by serial testing of blood glucose (A) and calculation of area under the curve (B). Intraperitoneal insulin tolerance test (0.75 U/kg) was conducted at 8 weeks of HFD feeding by serial testing of blood glucose (C) and calculation of area under the curve (D). Weekly body weights (E) normalized to individual baseline weight. Fasting blood glucose at 12 weeks of HFD feeding (F). Wild-type on standard rodent chow were included as controls (ND). (n = 10; *P ≤ 0.05 by treatment).

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