Figure 6 | Scientific Reports

Figure 6

From: Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating LANCL2 in skeletal muscle

Figure 6

ABA increases the metabolic activity of human skeletal myotubes ex vivo. Human skeletal myoblasts were differentiated into myotubes for 72 h. Cell were treated with ABA (0, 50, 100, 150 nM) and human insulin lispro (0, 100 nM) 1 h prior to assay. Glycolysis ATP rate (A), mitochondrial ATP rate (B), and total ATP rate (C) were measured by Seahorse XF Real-Time ATP Rate Assay. Glycogen synthesis rate was measured by solubilization of cells after 4 h incubation with ABA, labeled glucose and insulin (D) (n = 9; *P ≤ 0.05 relative to 0 nM).

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