Figure 4
From: Venom alkaloids against Chagas disease parasite: search for effective therapies
Effects of solenopsins in the polyphosphate chains accumulated by epimastigotes forms of Trypanosoma cruzi. After cultivation for 48 h in the absence (NEG) or presence of 0.3 µM of solenopsins from Solenopsis invicta (INV) or S. saevissima (SAE), CL-Brener epimastigotes were collected and the short chain (A) and long chain (B) polyphosphates (PolyP) were extracted and quantified as described in Methods. Bar plots indicate mean values where dots are the raw data (nmoles.10–7 parasites) of three independent experiments. Statistics: Results were compared by non-parametric Kruskal–Wallis, and treatments are grouped by statistical similarity at alpha = 0.05 where indicated with brackets. For details refer to supplementary R script file.
