Table 2 Number of patients achieving the minimal clinically important improvement (MCII) at 6 and 3 months.

From: Spa therapy with physical rehabilitation is an alternative to usual spa therapy protocol in symptomatic knee osteoarthritis

Definition of responder

Standard spa therapy

Spa-rehab therapy

Difference for responders (Δ: Spa-rehab therapy minus standard spa therapy)

N

(%)

N

(%)

Δ

[90%CI]

p (non-inferiority)

p (difference)

6 months

n = 130

 

n = 114

     

Composite MCII

86

(66.2)

66

(57.9)

− 0.08

(− 0.18 to 0.02)

0.14

0.18

Pain MCII

50

(45.9)

37

(39.4)

− 0.07

(− 0.18 to 0.05)

0.11

0.35

Function MCII

69

(56.1)

56

(50.0)

− 0.06

(− 0.17 to 0.05)

0.09

0.35

3 months

n = 135

 

n = 107

     

Composite MCII

76

(56.3)

75

(70.1)

0.14

(0.04 to 0.24)

 < 0.0001

0.03

Pain MCII

49

(36.3)

49

(45.8)

0.10

(− 0.01 to 0.22)

0.0001

0.14

Function MCII

64

(47.4)

55

(51.4)

0.04

(− 0.07 to 0.15)

0.002

0.57

  1. Composite MCII: achieving pain MCII defined for knee OA as ≥ 19.9 mm on a VAS pain scale (0–100), and/or function MCII defined for knee OA as ≥ 9.1 points on the WOMAC function subscale (0–100) and no knee surgery.
Back to article page