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Figure 1

From: Long-term effects of medical management on growth and weight in individuals with urea cycle disorders

Figure 1

Intrauterine development of 205 individuals with UCDs is unaffected. Z-scores of weight (A), length (B), and head circumference (C) of 205 individuals with UCDs at birth. Mean z-scores for weight (z-score: − 0.24), length (z-score: 0.14) and head circumference (z-score: − 0.13) are overall within the normal range. Various diseases do not differ with regard to weight (p = 0.20; ANOVA), length (p = 0.26; ANOVA), and head circumference (p = 0.11; ANOVA). Data are shown as median (black line) and mean (triangle), length of the box corresponds to interquartile range (IQR), upper and lower whiskers correspond to max. 1.5 × IQR, each point represents an outlier. Descriptive characteristics are presented separately in Supplementary Table S1. ASL-D, argininosuccinate lyase deficiency; ASS1-D, argininosuccinate synthetase 1 deficiency; fOTC-D, female ornithine transcarbamylase deficiency; mOTC-D, male ornithine transcarbamylase deficiency.

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