Figure 7
Global levels of 5mC, 5hmC, and fC in DNA isolated from lung tumors of female A/J mice (6 weeks of age) treated intraperitoneally with NNK, intranasally with LPS, or in combination. (a) Global epigenetic levels of 5mC, 5hmC, and fC. Data are expressed as percent of dC and represents mean values ± SD of at least three animals. (b) Gene levels of TET proteins and tumor suppressor genes changes in lung tumors of A/J mice. Data were calculated from qRT-PCR using the ΔΔCt method ± SD with three biological and three technical replicates.
