Figure 3
From: Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

Spexin levels are increased in obese participants displaying improvement of VO2 max due to exercise. Circulating levels of Spexin were measured by ELISA using plasma samples from obese people and segregated according to increased (responders, n = 33) or not (non-responders, n = 14) VO2 max levels after 3-month physical exercise. The P value was determined using a paired t-test for intragroup comparisons before and after exercise.