Table 7 Characteristics of all obese sorted based on spexin-responders after exercise.

From: Spexin as an indicator of beneficial effects of exercise in human obesity and diabetes

 

Non-responders (N = 19)

Responders (N = 28)

Markers

Pre

Post

Variation

P values

Pre

Post

Variation

P values

BMI (kg/m2)

34.23 ± 2.83

33.58 ± 3.74

− 0.65 ± 1.13

0.131

33.55 ± 2.00

32.94 ± 1.91

− 0.63 ± 0.97

0.087

Waist (cm)

103.57 ± 6.81

101.86 ± 7.02

− 1.71 ± 2.49

0.079

109.80 ± 6.73

107.68 ± 4.79

− 2.12 ± 3.21

0.068

Hip (cm)

114.79 ± 8.35

113.30 ± 9.05

− 1.49 ± 4.08

0.197

113.57 ± 6.09

111.48 ± 5.73

− 2.09 ± 6.75

0.252

PBF (%)

40.15 ± 5.05

38.88 ± 6.30

− 1.27 ± 1.86

0.037

35.37 ± 3.94

34.58 ± 4.10

− 0.79 ± 1.90

0.129

WBC10

6.68 ± 2.01

6.61 ± 2.40

− 0.07 ± 0.49

0.830

6.75 ± 1.58

6.77 ± 1.61

0.02 ± 0.58

0.951

SBP (mmHg)

112.86 ± 9.51

112.86 ± 7.56

0.00 ± 3.25

1.000

120.00 ± 12.06

121.50 ± 7.67

1.50 ± 4.35

0.546

DBP (mmHg)

74.29 ± 5.35

76.43 ± 6.27

2.14 ± 4.09

0.510

76.67 ± 4.92

74.75 ± 5.38

− 1.92 ± 2.15

0.425

Resting HR (beats/min)

78.57 ± 9.81

78.86 ± 12.92

0.29 ± 2.02

0.857

85.58 ± 6.22

78.00 ± 10.62

− 7.58 ± 12.14

0.045

VO2, max (ml/kg/min)

16.74 ± 3.59

18.13 ± 3.97

1.39 ± 1.84

0.091

18.49 ± 2.80

21.05 ± 4.02

2.56 ± 3.88

0.035

TC (mmol/l)

4.96 ± 1.16

5.01 ± 1.22

0.05 ± 0.27

0.753

5.01 ± 1.07

4.47 ± 0.89

− 0.54 ± 1.03

0.018

HDL (mmol/l)

1.25 ± 0.41

1.34 ± 0.55

0.09 ± 0.23

0.111

1.08 ± 0.23

1.04 ± 0.23

− 0.04 ± 0.16

0.063

LDL (mmol/l)

3.18 ± 1.00

3.22 ± 1.09

0.04 ± 0.39

0.835

3.17 ± 1.15

2.83 ± 0.86

− 0.34 ± 0.88

0.191

TG (mmol/l)

1.21 ± 0.49

1.31 ± 0.80

0.10 ± 0.36

0.493

1.42 ± 0.59

1.63 ± 0.88

0.21 ± 0.67

0.318

FBG (mmol/l)

7.02 ± 2.82

6.62 ± 1.93

− 0.40 ± 1.07

0.418

7.26 ± 3.13

7.51 ± 3.44

0.25 ± 0.83

0.562

HbA1c (%)

7.12 ± 2.13

6.61 ± 1.32

− 0.51 ± 0.72

0.113

7.46 ± 2.15

6.72 ± 1.40

− 0.74 ± 1.06

0.003

Insulin (ng/ml)

4.34 ± 1.59

3.47 ± 1.57

− 0.87 ± 1.70

0.090

4.57 ± 2.59

3.62 ± 1.96

− 0.95 ± 2.39

0.088

C-peptide (ng/ml)

5.80 ± 7.82

4.92 ± 5.08

− 0.88 ± 2.17

0.465

6.26 ± 9.88

4.98 ± 5.70

− 1.28 ± 2.62

0.217

HOMA-IR

1.46 ± 0.78

1.03 ± 0.57

− 0.43 ± 0.52

0.039

1.45 ± 0.93

1.06 ± 0.69

− 0.39 ± 0.81

0.045

hsCRP (μg/ml)

4.11 ± 3.27

0.70 ± 0.34

− 3.41 ± 3.21

0.076

4.11 ± 2.69

1.15 ± 0.74

− 2.96 ± 2.57

< 0.001

  1. Data are presented as the mean ± SD.
  2. BMI body mass index, PBF percent body fat, SBP systolic blood pressure, DBP diastolic blood pressure, HR heart rate, VO2, max maximum oxygen consumption, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, TG triglyceride, FBG fasting blood glucose, HbA1c hemoglobin A1c, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, hsCRP high-sensitivity C-reactive protein.
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