Figure 2 | Scientific Reports

Figure 2

From: A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer’s disease

Figure 2

SNP-based results of ADNI-1. (A) The classification performance of SNP based analyses performed in ADNI-1 considering two classification tasks: AD vs. healthy controls (cases@controls) or 1/2 APOEe4 vs. 0 APOEe4 carriers (APOEe4 task). B. ACC, Balanced Accuracy; MCC, Matthews Correlation Coefficient; #genes*, number of genes or intergenic regions. (B) Balanced accuracy distribution plots of the regular (light blue) and the permutation batches (red) related to chromosomes 6 and 20 in the cases@controls task. (C) Balanced Accuracy distribution plots of the regular (light blue) and the permutation (red) batches related to chromosomes 1, 3, 9, 19 and 20 in the APOEe4 task.

Back to article page