Figure 3
Spleen size correlates with human T cell chimerism. (a) Gross examination of spleens was conducted 7 days after surgery. (b) Measurement of spleen length of 7–8 mice per group reveals no significant reduction in size after injury (30 mice total). (c) Instead, spleen length was associated with frequency of hCD45+ and hCD3+ cells in the spleen and peripheral blood (Regression analysis, p < 0.05 for all comparisons). (d) No relationship exists between treatment group and human chimerism in the spleen or inguinal lymph nodes (8–9 mice per group for analysis of spleen and 4–5 mice per group for lymph nodes).
