Figure 1 | Scientific Reports

Figure 1

From: Cardiomyocyte-specific deletion of GCN5L1 in mice restricts mitochondrial protein hyperacetylation in response to a high fat diet

Figure 1The alternative text for this image may have been generated using AI.

Characterization of mitochondrial acetylation in WT and GCN5L1 cKO animals. (A) Genotype and breeding scheme of WT and GCN5L1 cKO transgenic mice. (B) Diet and tamoxifen (Tam) injection schedule of WT and GCN5L1 cKO mice. (C, D) Overall acetylation of mitochondria isolated from cardiac tissues was greatly increased in HFD WT animals, which was significantly attenuated in HFD cKO mice. Values are expressed as means ± SD, n = 5, *P < 0.05 versus WT LFD, $P < 0.05 versus cKO LFD, #P < 0.05 versus WT HFD.

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