Table 1 Anthropometric and metabolic characteristics of the study subjects.

From: Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

 

Lean subjects

n = 100

Obese subjects

n = 100

t/z

p

Age (years)

30 ± 7

36 ± 8

-5.1

 < 0.00001

Weight (kg)

62 ± 9

91 ± 14

-10.5

 < 0.0001

BMI (kg/m2)

22.5 ± 2

34 ± 4

-16.0

 < 0.0001

SBP (mmHg)

107 ± 10

114 ± 9

-2.6

0.01

DBP (mmHg)

71 ± 8

77 ± 6.5

-3.2

0.001

Glucose (mg/dL)

85 ± 11

91 ± 12

-1.1

NS

Total cholesterol (mg/dL)

175 ± 32

184 ± 36

-0.4

NS

HDL-c (mg/dL)

57 ± 14

46 ± 14

3.9

0.001

LDL-c (mg/dL)

98 ± 29

105 ± 41

-1.02

NS

Triglycerides (mg/dL)

89 (61–123)

138 (95–180)

-2.98

 < 0.01

Insulin (µIU/mL)

8.5 (6–10)

15 (10–21)

-4.32

 < 0.0001

Acylated ghrelin (pg/mL)

112 (84–160)

76 (37–132)

-2.78

 < 0.01

Leptin (ng/mL)

16 (8–30)

47 (27–65)

-3.68

 < 0.001

HOMA-IR

1.7 (1.3–2.2)

3.0 (2.3–5)

-4.2

 < 0.0001

MNA-1 (ng/mL)

9 (8–15)

13 (8–21)

-2.1

NS

REE (Kcal/day)

1,510 ± 278

1745 ± 364

-3.5

 < 0.001

  1. The values are expressed as the means ± SD or medians and interquartile range. The differences between lean and obese subjects were evaluated using Student’s t-test or Mann–Whitney U test. SBP = systolic blood pressure, DBP = diastolic blood pressure, BMI = body mass index, HDL = high-density lipoproteins, LDL = low-density lipoproteins, HOMA-IR = homeostasis model assessment insulin resistance, MNA-1 = N1-methylnicotinamide, REE = resting energy expenditure. P values adjusted for the effects of age.
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