Table 4 Anthropometric and metabolic characteristics of rs1941404 NNMT genotypes (recessive model).

From: Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

 

TT/CT

n = 171

CC

n = 25

t/z

P

Weight (kg)

75 ± 19

79 ± 18

-0.91

NS

BMI (kg/m2)

28 ± 7

30.8 ± 7

-1.85

0.06

Glucose (mg/dL)

88 ± 11

89 ± 14

-0.24

NS

Total cholesterol (mg/dL)

179 ± 34

179 ± 39

-0.01

NS

HDL-c (mg/dL)

52 ± 15

50 ± 14

0.66

NS

LDL-c (mg/dL)

102 ± 30

97 ± 46

0.69

NS

Triglycerides (mg/dL)

109 (76–156)

97 (78–128)

1.01

NS

Insulin (µIU/ml)

10.3 (7.3 – 15)

10.3 (7.5–13)

0.015

NS

Acylated ghrelin (pg/mL)

107 (61–147)

90 (61–136)

-0.55

NS

Leptin (ng/mL)

25.6 (13–48)

40.9 (15–63)

-1.9

0.05

HOMA-IR

2.2 (1.6–3.2)

2.3 (1.7–3.3)

0.23

NS

MNA-1 (ng/mL)

9.4 (7.8–14.9)

13.3 (7.8–20.8)

-1.18

NS

REE (Kcal/day)

1628 ± 351

1596 ± 298

0.43

NS

  1. The values are expressed as the means ± SD or medians and interquartile range. The differences between lean and obese subjects were evaluated using Student’s t-test or Mann–Whitney U test. BMI = body Mass Index, HDL = high-density lipoproteins, LDL = low-density lipoproteins, HOMA-IR = homeostasis model assessment insulin resistance, MNA-1 = N1-methylnicotinamide, REE = resting energy expenditure.
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