Table 7 GMDR analysis of rs694539 and rs1941404 NNMT, rs1421085 FTO, and rs3751723 IRX3 for obesity.

From: Associations of nicotidamide-N-methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects

Phenotypes

Model

Testing accuracy (%)

CVC

OR (95% CI)

p-value

Obese/non-obese

rs694539, rs1941404, rs1421085, rs3751723

0.674

5/5

4.62 (1.75–12.10)

0.001

Obese/non-obese

rs694539, rs1941404, rs1421085, rs3751723*

0.744

5/5

9.86 (1.42–68.40)

 < 0.05

  1. * Predictors: gender, age, HDL-c, LDL-c, triglycerides, REE, acylated ghrelin, leptin, HOMA-IR.
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