Figure 3

Comparative phenotypes in Adad1^tm1Reb and Adad1^em2 males. Quantification of wildtype and homozygous Adad1 mutant (A) offspring sired (N = 3) and (B) epididymal sperm concentration (N ≥ 4). (C) Representative comparison of mature spermatozoa morphology between wildtype, Adad1^tm1Reb, and Adad1^em2males. (D) Quantification of morphologically abnormal epididymal sperm in homozygous mutant Adad1^tm1Reb and Adad1^em2 adult males. Error bars—standard deviation, * p-value < 0.05, ** p-value < 0.005, *** p-value < 0.0001.